Journal article
Celogentin mimetics as inhibitors of tubulin polymerization
VJ Thombare, JA Holden, EC Reynolds, NM O'Brien-Simpson, CA Hutton
Journal of Peptide Science | WILEY | Published : 2020
DOI: 10.1002/psc.3239
Abstract
Bicyclic analogues of celogentin C have been synthesized in which the side chain–side chain cross-links are replaced by thioether bonds. Several of the simplified bicyclic peptides displayed potent inhibition of tubulin polymerization.
Related Projects (2)
Grants
Awarded by Australian Research Council
Funding Acknowledgements
Australian Research Council, Grant/Award Numbers: DP150100692 and DP180101804